| Name | Address | ZIP | Phone | Reviews |
| » Affordable Suites of America | 530 Woody Jones Boulevard | 29501 | (843)679-3344
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| » Best Western | 1808 West Lucas Street | 29501 | (843)678-9140
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| » Best Western Inn | 1808 West Lucas Street | 29501 | (843)678-9292
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| » Budget Motel | 2833 East Palmetto Street | 29506 | (843)662-6375
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| » Coffee Beanery | 1914 West Lucas Street | 29501 | (843)665-2575
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| » Colonial Inn | 415 South Irby Street | 29501 | (843)662-1486
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| » Comfort Inn | 1-95 And Us # 52 | 29501 | (843)665-4558
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| » Country Hearth Inn & Suites | 831 South Irby Street | 29501 | (843)662-9421
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| » Country Inn & Suites Florence | 1739 Mandeville Road | 29501 | (843)317-6616
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| » Courtyard by Marriott - Florence | 2680 Hospitality Boulevard | 29501 | (843)662-7066
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| » Days Inn Florence SC | I 95 And US 76 Exit 157 | 29501 | (843)665-8550
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| » Days Inn of Florence | Highway 52 And I # 95 | 29501 | (843)665-4444
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| » Econo Lodge North | 1811 West Lucas Street | 29501 | (843)665-8558 | Read/Add review |
| » Economy Inn | 5235 East Palmetto Street | 29506 | (843)662-2325
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| » Fairfield Inn by Marriott | I95 At I20 Business | 29501 | (843)669-1666
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| » First Florence Corporation | 1914 West Lucas Street | 29501 | (843)669-0855
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| » Florence Howard Johnson Express Inn - Florence- SC | 3821 Bancroft Rd. 1-95 & U.S. 76 | 29501 | (843)664-9494
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| » Florence Motel | 414 South Irby Street | 29501 | (843)662-1428
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| » GuestHouse Intl Florence | 2001 West Lucas Street | 29503 | (843)669-1921
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| » Hampton Inn & Suites Florence-Civic Cent | 3000 West Radio Drive | 29501 | (843)629-9900
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| » Hampton Inn Florence-North | 1826 West Lucas Street | 29501 | (843)662-7000
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| » Holiday Inn | US 52 & I-95 | 29501 | (803)669-3251 | Read/Add review |
| » Holiday Inn Express | 150 Dunbarton Drive | 29501 | (843)664-0346
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| » Holiday Inn Express Hotel & Suites | 2101 Florence Harllee Boulevard | 29506 | (843)629-9779 | Read/Add review |
| » Holiday Inn Express Hotels | 150 Dunbarton Drive | 29501 | (843)664-2400 | Read/Add review |
| » Holiday Inn Hotel & Suites | 2101 Florence Harlle Boulevard | 29506 | (843)661-7142
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| » Holiday Inn Hotel and Suites | 2101 Florence Harllee Blv | 29506 | (843)629-9774 | Read/Add review |
| » Howard Johnson | 3821 Bancroft Road | 29501 | (803)664-9494
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| » Magnolia Dining Room | 3311 Meadors Road | 29501 | (843)669-4171
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| » Magnolia Manor | 2212 South Irby Street | 29505 | (843)661-6801
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| » Marriott | 2670 Hospitality Boulevard | 29501 | (843)317-9025
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| » Microtel | 1912 Enterprise Drive | 29501 | (843)629-9522
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| » Motel 6 | 1834 West Lucas Street | 29501 | (843)667-6100
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| » Motel Associates | 831 South Irby Street | 29501 | (843)669-3232
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| » Ramada Inn | 2038 W Lucas St | 29501 | (803)669-4241
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| » Ramada Inn | 2038 W Lucas St | 29501 | (843)669-4241
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| » Ramada Inn Sales Director | I-95 & US52 | 29501 | (843)667-4327
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| » Red Roof Inn Florence | 2690 David H McLeod Blvd # 160-A | 29501 | (843)678-9000
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| » Rodeway Inn I-95 | 3024 Tv Road | 29501 | (843)669-1715 | Read/Add review |
| » Sleep Inn | 1833 Florence Park Drive | 29501 | (843)679-3055
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| » Sleep Inn Florence | 1833 Florence Park Drive | 29501 | (843)662-8558 | Read/Add review |
| » SpringHill Suites Florence | 2670 Hospitality Boulevard | 29501 | (800)287-9400
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| » Star Motel | 2917 East Palmetto Street | 29506 | (843)669-6472
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| » Super 8 Motel | 1832 West Lucas Street | 29501 | (843)661-7267
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| » Thunderbird Inn | 2004 West Lucas Street | 29501 | (843)669-1611
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| » Uptown Motel | 311 South Irby Street | 29501 | (843)662-0306
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| » Wingate Inn - Florence | 2123 W Lucas St | 29501 | (843)629-1111
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| » Young Edward L | 3339 Meadors Road | 29501 | (843)669-2900
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